Publication Type:Journal Article
Source:Biomed Data J. , Volume 1, Issue 2, p.13-18 (2015)
Keywords:C-reactive protein, Ischemic stroke, Neuroprotection, Outcomes, Thyroid hormones
Ischemic stroke remains a serious public health problem, associated with significant mortality and morbidity. Accurate and timely prognostication of functional and patient-oriented outcomes of stroke victims is important for improving patient outcomes and for optimized use of healthcare resources. A growing body of evidence suggests that the Hypothalamic-Pituitary-Thyroid axis hormones can exert neuro-protective properties under ischemic conditions and can be employed for outcome prediction in severely ill patients, including stroke victims. The goal of the present study was to investigate the association of the HPT-axis and C-reactive protein (CRP) serum concentrations with clinical stroke severity and with functional and cognitive discharge outcomes. Here we present a dataset from prospective observational cohort study of 88 acute ischemic stroke patient admitted within 24 hours after stroke symptom onset and without thyroid gland disorders. All patients received treatment according to the existing guidelines. The dataset includes socio-demographic and clinical characteristics, clinical stroke severity assessment (Scandinavian Stroke Scale), serum concentrations of tri-iodothyronine, thyroxin, thyroid stimulating hormone and CRP that were evaluated within 24 hours after hospital admission. Functional outcome (modified Rankin scale) and cognitive outcome (Mini Mental State Examination) assessments were performed at hospital discharge.
Interested readers can download both the paper and the dataset it describes below, under the respective Creative Commons licence.