Publication Type: Journal Article
Source: Biomed Data J, Volume 1, Issue 3, p.37-40 (2015)
Keywords: cardiac remodelling
, Heart Failure
, myocardial infarction
Open-access datasets for cardiac remodelling after myocardial infarction in any species have not been reported, and this limits the development of systems approaches in medicine. In this paper, we present a dataset from echocardiographic assessment of male C57BL mice that were subjected to acute myocardial infarction. We present measurements that show the deterioration of global left ventricular (LV) function, regional function, development of LV dilation and hypertrophy. At the same time, we present measurements showing the degree of cardiac injury as well as the development of pulmonary congestion. Importantly, LV dilation—a hallmark of cardiac remodelling—does not develop in all subjects, and this is only partly explained by the degree of cardiac injury.